Anderson had previously worked as a cameraman on a piece with Boone about eight years before starting work on Fuck.After confirming Boone, Bill Maher and Janeane Garofalo on Fuck, it became easier for Anderson to confirm other interviewees.
He acknowledged that there are terms considered by society more vulgar than "fuck", but said that this particular word creates controversy and dialogue.
There were inherent problems with this approach, including an inability to advertise the true title in mainstream media such as The New York Times and Los Angeles Times (they used four asterisks instead), although the real title might be permitted in alternative newspapers such as LA Weekly.
Anderson explained that although the title of his documentary was Fuck, he allowed alternate designations using an asterisk.
The documentary includes commentary from film and television writers Kevin Smith and Steven Bochco; comedians Janeane Garofalo, Bill Maher, Drew Carey and Billy Connolly; musicians Chuck D, Alanis Morissette and Ice T; political commentators Alan Keyes and Pat Boone; and journalists Michael Medved and Judith Martin. Fuck includes songs with similarly themed titles, including "Shut Up and Fuck" by American hard rock band Betty Blowtorch, "Fucking Fucking Fuck" by Splatpattern and "I Love to Say Fuck" by American horror punk supergroup Murderdolls.
Journalist Sam Peczek of Culture Wars compared the film's music to that in softcore pornography, and observed that the soundtrack was broad in scope and helped accentuate the film's content.